Fundamental Science Title

We believe that bioengineering should be informed by state-of-the-art fundamental science: biology, chemistry, and physics. Our group has expertise in a broad range of fundamental science, especially soft matter physics. Over the two decades, there has been a significant conceptual renovation of electrostatics in aqueous media, and we have contributed to our current understanding of electrostatic interactions in the context of biological systems.

Some examples of our work in the above areas include liquid crystalline phase transitions in stereocilia and their role in deafness (Purdy et al PRL 2007), movies of femtosec hydration dynamics at sub-Angstrom resolution (Coridan et al PRL 2009), the role of counterions in like-charge attraction between polyelectrolytes (Angelini et al PNAS 2003; Angelini et al PNAS 2006), the drying of DNA droplets and potential impact on gene chips (Smalyukh et al PRL 2006), biomineralization of inorganic crystals with control of crystallographic orientation (Liang et al, JACS 2003; Liang et al, JACS 2004), and the design of non-stick antimicrobials tailored for cystic fibrosis airways (Sanders PRL, 2005; Sanders PNAS, 2007).

General references for our work on these areas are listed below. The papers are available on our publications page.

  • Coridan et al, PRE 2012
  • Shin et al, PRL 2009
  • Lai et al, PRL 2008
  • Purdy et al, PRL 2007
  • Lai et al, PRL 2007
  • Sanders et al, PNAS 2007
  • Smalyukh et al, PRL 2006
  • Angelini et al, PNAS 2006
  • Liang et al, PNAS 2005
  • Sanders et al, PRL 2005
  • Yang et al, Nature Mat 2004
  • Angelini et al, PNAS 2003
  • Butler et al, PRL 2003
  • Wong et al, PRL 2003
  • Wong et al, Science 2000
  • Mol et al, PRL 1997
  • Wong et al, Nature 1997
  • Wong et al, PRB 1996
  • Wong et al, PRL 1996

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